This white paper explores the development and implementation of Digital Health Applications (DiGA) in Portugal, aiming to create a sustainable framework for their adoption within the healthcare system. It highlights the challenges and opportunities in the digital health ecosystem, particularly focusing on how digital therapeutics can be integrated into national health services. The paper draws inspiration from Germany’s DiGA model, recommending steps for collaboration, value-based healthcare, and improving digital literacy to ensure successful implementation. It also emphasizes the importance of developing clear regulatory pathways and aligning reimbursement models to support digital health innovation across Portugal.